BDBM50390577 CHEMBL2069482

SMILES: N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1

InChI Key: InChIKey=STGSGLZBXACHOX-INIZCTEOSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50390577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50390577 (CHEMBL2069482) Show SMILES N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 |r| Show InChI InChI=1S/C19H18N4O2/c20-16(10-13-4-2-1-3-5-13)18(24)23-17-11-15(12-22-19(17)25)14-6-8-21-9-7-14/h1-9,11-12,16H,10,20H2,(H,22,25)(H,23,24)/t16-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation counting				Bioorg Med Chem Lett 22: 6218-23 (2012) Article DOI: 10.1016/j.bmcl.2012.08.015 BindingDB Entry DOI: 10.7270/Q2CN751R
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Mus musculus)	BDBM50390577 (CHEMBL2069482) Show SMILES N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 |r| Show InChI InChI=1S/C19H18N4O2/c20-16(10-13-4-2-1-3-5-13)18(24)23-17-11-15(12-22-19(17)25)14-6-8-21-9-7-14/h1-9,11-12,16H,10,20H2,(H,22,25)(H,23,24)/t16-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR142 assessed as inositol phosphate accumulation				Bioorg Med Chem Lett 22: 5942-7 (2012) Article DOI: 10.1016/j.bmcl.2012.07.063 BindingDB Entry DOI: 10.7270/Q2VH5PXT
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50390577 (CHEMBL2069482) Show SMILES N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 |r| Show InChI InChI=1S/C19H18N4O2/c20-16(10-13-4-2-1-3-5-13)18(24)23-17-11-15(12-22-19(17)25)14-6-8-21-9-7-14/h1-9,11-12,16H,10,20H2,(H,22,25)(H,23,24)/t16-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...				Bioorg Med Chem Lett 22: 5942-7 (2012) Article DOI: 10.1016/j.bmcl.2012.07.063 BindingDB Entry DOI: 10.7270/Q2VH5PXT
					More data for this Ligand-Target Pair