BDBM50390641 CHEMBL2069714
SMILES: Cc1ccc2nc(sc2c1)-c1csc(c1)S(N)(=O)=O
InChI Key: InChIKey=SOGLIJJXPISIRD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human)) | BDBM50390641 (CHEMBL2069714) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay | Bioorg Med Chem Lett 22: 5919-23 (2012) Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN | |||||||||||
More data for this Ligand-Target Pair |