BDBM50391635 CHEMBL2147947

SMILES: OC(=O)[C@H](Cc1ccc(OCCc2ccccc2)cc1)NC(=O)c1ccccc1

InChI Key: InChIKey=XXLWVDAYISNRTI-QFIPXVFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50391635 (CHEMBL2147947) Show SMILES OC(=O)[C@H](Cc1ccc(OCCc2ccccc2)cc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H23NO4/c26-23(20-9-5-2-6-10-20)25-22(24(27)28)17-19-11-13-21(14-12-19)29-16-15-18-7-3-1-4-8-18/h1-14,22H,15-17H2,(H,25,26)(H,27,28)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.53E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of HDAC8 after 45 mins by microplate fluorometric analysis				Bioorg Med Chem 20: 5738-44 (2012) Article DOI: 10.1016/j.bmc.2012.08.014 BindingDB Entry DOI: 10.7270/Q2988849
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50391635 (CHEMBL2147947) Show SMILES OC(=O)[C@H](Cc1ccc(OCCc2ccccc2)cc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H23NO4/c26-23(20-9-5-2-6-10-20)25-22(24(27)28)17-19-11-13-21(14-12-19)29-16-15-18-7-3-1-4-8-18/h1-14,22H,15-17H2,(H,25,26)(H,27,28)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of MMP2 using BML-P125-9090 as substrate after 30 mins by microplate reader analysis				Bioorg Med Chem 20: 5738-44 (2012) Article DOI: 10.1016/j.bmc.2012.08.014 BindingDB Entry DOI: 10.7270/Q2988849
					More data for this Ligand-Target Pair