BDBM50391970 CHEMBL2152279

SMILES: CN(C)CCOc1ccc(cc1N)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key: InChIKey=NOKOLFLNTAOTJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50391970 (CHEMBL2152279) Show SMILES CN(C)CCOc1ccc(cc1N)-c1cnc2[nH]cc(-c3ccncc3)c2c1 Show InChI InChI=1S/C22H23N5O/c1-27(2)9-10-28-21-4-3-16(12-20(21)23)17-11-18-19(14-26-22(18)25-13-17)15-5-7-24-8-6-15/h3-8,11-14H,9-10,23H2,1-2H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate				J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3
					More data for this Ligand-Target Pair