null

SMILES: OC1(CC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=QYUJNLGEANWSCR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50392683 (CHEMBL2151352) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H14N2O5/c21-14(10-18(25)15(22)19-17(24)20-16(18)23)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,25H,10H2,(H2,19,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50392683 (CHEMBL2151352) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H14N2O5/c21-14(10-18(25)15(22)19-17(24)20-16(18)23)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,25H,10H2,(H2,19,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50392683 (CHEMBL2151352) Show SMILES OC1(CC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C18H14N2O5/c21-14(10-18(25)15(22)19-17(24)20-16(18)23)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,25H,10H2,(H2,19,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	517	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...				Eur J Med Chem 58: 368-76 (2012) Article DOI: 10.1016/j.ejmech.2012.09.036 BindingDB Entry DOI: 10.7270/Q28053QN
					More data for this Ligand-Target Pair