null
SMILES: Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCO1
InChI Key: InChIKey=HZMDOJYDKAZVJW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human)) | BDBM50393496 (CHEMBL2159935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate | J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human)) | BDBM50393496 (CHEMBL2159935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrate | J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human)) | BDBM50393496 (CHEMBL2159935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate | J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0 | |||||||||||
More data for this Ligand-Target Pair |