null

SMILES: C(Nc1cc(ncn1)N1CCOCC1)c1ccccc1

InChI Key: InChIKey=RTKDLWACQIHAKB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50393990 (CHEMBL2158433) Show SMILES C(Nc1cc(ncn1)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C15H18N4O/c1-2-4-13(5-3-1)11-16-14-10-15(18-12-17-14)19-6-8-20-9-7-19/h1-5,10,12H,6-9,11H2,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen ass...				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50393990 (CHEMBL2158433) Show SMILES C(Nc1cc(ncn1)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C15H18N4O/c1-2-4-13(5-3-1)11-16-14-10-15(18-12-17-14)19-6-8-20-9-7-19/h1-5,10,12H,6-9,11H2,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen as...				Bioorg Med Chem Lett 22: 6665-70 (2012) Article DOI: 10.1016/j.bmcl.2012.08.101 BindingDB Entry DOI: 10.7270/Q27H1KPB
					More data for this Ligand-Target Pair