BDBM50394751 CHEMBL2165863

SMILES: Clc1ccc(\C=C2/N=C(OC2=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=XMWNDTVHTNHYFX-WQRHYEAKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50394751 (CHEMBL2165863) Show SMILES Clc1ccc(\C=C2/N=C(OC2=O)c2ccc3ccccc3c2)cc1 |c:7| Show InChI InChI=1S/C20H12ClNO2/c21-17-9-5-13(6-10-17)11-18-20(23)24-19(22-18)16-8-7-14-3-1-2-4-15(14)12-16/h1-12H/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL2-DE3 incubated 10 mins before substrate addition by fluorescence spectrophotom...				J Med Chem 55: 2597-605 (2012) Article DOI: 10.1021/jm201497k BindingDB Entry DOI: 10.7270/Q20P115J
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50394751 (CHEMBL2165863) Show SMILES Clc1ccc(\C=C2/N=C(OC2=O)c2ccc3ccccc3c2)cc1 |c:7| Show InChI InChI=1S/C20H12ClNO2/c21-17-9-5-13(6-10-17)11-18-20(23)24-19(22-18)16-8-7-14-3-1-2-4-15(14)12-16/h1-12H/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human 5-LOX in A23187-induced human whole blood assessed as reduction in LTB4 production pre-incubated for 20 mins before A23187 additi...				J Med Chem 55: 2597-605 (2012) Article DOI: 10.1021/jm201497k BindingDB Entry DOI: 10.7270/Q20P115J
					More data for this Ligand-Target Pair