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BDBM50396902 CHEMBL2170696

SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O

InChI Key: InChIKey=FTFPIHQJPLQKAJ-PRFXMNKFSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396902   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))		BDBM50396902
PNG
(CHEMBL2170696)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O |r|
Show InChI InChI=1S/C49H64N8O6S2/c1-29(2)22-37(44(52)58)53-46(60)38(23-30(3)4)55-49(63)41(26-33-28-65-43-20-11-9-17-35(33)43)57-47(61)39(24-31-14-6-5-7-15-31)56-48(62)40(54-45(59)36(51)18-12-13-21-50)25-32-27-64-42-19-10-8-16-34(32)42/h5-11,14-17,19-20,27-30,36-41H,12-13,18,21-26,50-51H2,1-4H3,(H2,52,58)(H,53,60)(H,54,59)(H,55,63)(H,56,62)(H,57,61)/t36-,37-,38-,39-,40+,41+/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 9.40n/an/an/an/a



Universit£t Leipzig

Curated by ChEMBL


Assay Description
Inverse agonist activity at human ghrelin receptor expressed in COS 7 cells using [2-3H]myo-inositol by inositol triphosphate turnover assay

J Med Chem 55: 7437-49 (2012)


Article DOI: 10.1021/jm300414b
BindingDB Entry DOI: 10.7270/Q26M37Z8
More data for this
Ligand-Target Pair