BDBM50397584 CHEMBL2171506

SMILES: CCCOc1nc2ccccc2cc1-c1cc(C(C)C)c2ccc(nc2c1)N1CCOCC1

InChI Key: InChIKey=NNSULNYBTSFDTD-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50397584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50397584 (CHEMBL2171506) Show SMILES CCCOc1nc2ccccc2cc1-c1cc(C(C)C)c2ccc(nc2c1)N1CCOCC1 Show InChI InChI=1S/C28H31N3O2/c1-4-13-33-28-24(16-20-7-5-6-8-25(20)30-28)21-17-23(19(2)3)22-9-10-27(29-26(22)18-21)31-11-14-32-15-12-31/h5-10,16-19H,4,11-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bcl-XL interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50397584 (CHEMBL2171506) Show SMILES CCCOc1nc2ccccc2cc1-c1cc(C(C)C)c2ccc(nc2c1)N1CCOCC1 Show InChI InChI=1S/C28H31N3O2/c1-4-13-33-28-24(16-20-7-5-6-8-25(20)30-28)21-17-23(19(2)3)22-9-10-27(29-26(22)18-21)31-11-14-32-15-12-31/h5-10,16-19H,4,11-15H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bcl2 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50397584 (CHEMBL2171506) Show SMILES CCCOc1nc2ccccc2cc1-c1cc(C(C)C)c2ccc(nc2c1)N1CCOCC1 Show InChI InChI=1S/C28H31N3O2/c1-4-13-33-28-24(16-20-7-5-6-8-25(20)30-28)21-17-23(19(2)3)22-9-10-27(29-26(22)18-21)31-11-14-32-15-12-31/h5-10,16-19H,4,11-15H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM50397584 (CHEMBL2171506) Show SMILES CCCOc1nc2ccccc2cc1-c1cc(C(C)C)c2ccc(nc2c1)N1CCOCC1 Show InChI InChI=1S/C28H31N3O2/c1-4-13-33-28-24(16-20-7-5-6-8-25(20)30-28)21-17-23(19(2)3)22-9-10-27(29-26(22)18-21)31-11-14-32-15-12-31/h5-10,16-19H,4,11-15H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bfl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair