BDBM50398143 CHEMBL2177224

SMILES: Fc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1

InChI Key: InChIKey=GQEGYMPXVAKBAF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398143 (CHEMBL2177224) Show SMILES Fc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C27H19FN2O3/c28-23-13-11-19(14-24(23)30-27(32)17-6-2-1-3-7-17)29-20-10-12-22-25(15-20)33-16-18-8-4-5-9-21(18)26(22)31/h1-15,29H,16H2,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair