BDBM50399053 CHEMBL2178852

SMILES: COc1cccc(Oc2cc(C)nc(n2)-c2ccccc2)c1

InChI Key: InChIKey=HZWISPZEEHDUMF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (MIF) (Plasmodium falciparum)	BDBM50399053 (CHEMBL2178852) Show SMILES COc1cccc(Oc2cc(C)nc(n2)-c2ccccc2)c1 Show InChI InChI=1S/C18H16N2O2/c1-13-11-17(22-16-10-6-9-15(12-16)21-2)20-18(19-13)14-7-4-3-5-8-14/h3-12H,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...				J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7
					More data for this Ligand-Target Pair