BDBM50401307 CHEMBL2205208

SMILES: COc1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1ccncc1

InChI Key: InChIKey=IABIHFIXBRDJEJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50401307 (CHEMBL2205208) Show SMILES COc1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1ccncc1 Show InChI InChI=1S/C20H19N5O2/c1-27-19-16-13-25(20(26)22-15-5-3-2-4-6-15)12-9-17(16)23-18(24-19)14-7-10-21-11-8-14/h2-8,10-11H,9,12-13H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	422	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 22: 5903-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.072 BindingDB Entry DOI: 10.7270/Q23J3F3X
					More data for this Ligand-Target Pair