BDBM50403044 CHEMBL179241
SMILES: CCCCCCCC[C@@]1(C)SC(=O)C(CC=C)(CC=C)C1=O
InChI Key: InChIKey=AGBIARLSXFYGHC-GOSISDBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid synthase (Homo sapiens (Human)) | BDBM50403044 (CHEMBL179241) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins University Curated by ChEMBL | Assay Description Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells | J Med Chem 48: 946-61 (2005) Article DOI: 10.1021/jm049389h BindingDB Entry DOI: 10.7270/Q2NS0XN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carnitine O-palmitoyltransferase 1, liver isoform (Homo sapiens (Human)) | BDBM50403044 (CHEMBL179241) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Increase in CPT1 activity in human MCF7 cells assessed as increase in radiolabeled palmitoylcarnitine | J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ | |||||||||||
More data for this Ligand-Target Pair |