BDBM50405206 CHEMBL298353

SMILES: Cc1c(O)cc(CC(=O)c2ccccc2)oc1=O

InChI Key: InChIKey=KOTFPNOCGYLHOZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsin (Homo sapiens (Human))	BDBM50405206 (CHEMBL298353) Show SMILES Cc1c(O)cc(CC(=O)c2ccccc2)oc1=O Show InChI InChI=1S/C14H12O4/c1-9-12(15)7-11(18-14(9)17)8-13(16)10-5-3-2-4-6-10/h2-7,15H,8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.13E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against bovine Chymotrypsinogen expressed as inhibitory constant				J Med Chem 28: 1828-32 (1986) BindingDB Entry DOI: 10.7270/Q28S4R4F
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50405206 (CHEMBL298353) Show SMILES Cc1c(O)cc(CC(=O)c2ccccc2)oc1=O Show InChI InChI=1S/C14H12O4/c1-9-12(15)7-11(18-14(9)17)8-13(16)10-5-3-2-4-6-10/h2-7,15H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.77E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte elastase (HL elastase) expressed as inhibitory constant				J Med Chem 28: 1828-32 (1986) BindingDB Entry DOI: 10.7270/Q28S4R4F
					More data for this Ligand-Target Pair
Elastase (Sus scrofa (Pig))	BDBM50405206 (CHEMBL298353) Show SMILES Cc1c(O)cc(CC(=O)c2ccccc2)oc1=O Show InChI InChI=1S/C14H12O4/c1-9-12(15)7-11(18-14(9)17)8-13(16)10-5-3-2-4-6-10/h2-7,15H,8H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.14E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic elastase (PP elastase) expressed as inhibitory constant				J Med Chem 28: 1828-32 (1986) BindingDB Entry DOI: 10.7270/Q28S4R4F
					More data for this Ligand-Target Pair