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SMILES: O=C(NCCN1CCC(Cc2ccccc2)CC1)c1ccccc1

InChI Key: InChIKey=ZLVPRFDTUNVSKD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406151   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50406151
PNG
(CHEMBL101388)
Show SMILES O=C(NCCN1CCC(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c24-21(20-9-5-2-6-10-20)22-13-16-23-14-11-19(12-15-23)17-18-7-3-1-4-8-18/h1-10,19H,11-17H2,(H,22,24)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.55E+3n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum

J Med Chem 33: 2970-6 (1990)


BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair