BDBM50406656 CHEMBL81039

SMILES: COc1ccc(OC)c(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c1

InChI Key: InChIKey=IWEHBWQRQSXYND-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406656 (CHEMBL81039) Show SMILES COc1ccc(OC)c(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c1 Show InChI InChI=1S/C24H33N3O4/c1-29-20-10-11-23(30-2)22(17-20)26-24(28)25-12-7-15-31-21-9-6-8-19(16-21)18-27-13-4-3-5-14-27/h6,8-11,16-17H,3-5,7,12-15,18H2,1-2H3,(H2,25,26,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.				J Med Chem 35: 2446-51 (1992) BindingDB Entry DOI: 10.7270/Q2V9898T
					More data for this Ligand-Target Pair