BDBM50408214 CHEMBL4163852

SMILES: Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1

InChI Key: InChIKey=XFCFHDRWNFQOJT-UHFFFAOYSA-N

Data: 2 KI  4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50408214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 mins				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 mins				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD12 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assay				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM50408214 (CHEMBL4163852) Show SMILES Fc1ccc(Cn2ccc(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1 Show InChI InChI=1S/C26H27FN2O2/c27-21-14-12-19(13-15-21)18-29-17-16-23(20-8-4-3-5-9-20)24(26(29)31)25(30)28-22-10-6-1-2-7-11-22/h3-5,8-9,12-17,22H,1-2,6-7,10-11,18H2,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...				Eur J Med Chem 154: 155-171 (2018) Article DOI: 10.1016/j.ejmech.2018.05.019 BindingDB Entry DOI: 10.7270/Q24F1T87
					More data for this Ligand-Target Pair