BDBM50408672 CHEMBL144000
SMILES: CNCCCCCCN(C)Cc1cccc(c1)C(=O)N(C)CCCCCCN(C)c1nc(N)c2cc(OC)c(OC)cc2n1
InChI Key: InChIKey=VDSSOFQYDAIUHS-UHFFFAOYSA-N
Data: 3 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50408672![]() (CHEMBL144000) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 14.4 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50408672![]() (CHEMBL144000) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.91 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of the norepinephrine induced contraction of rat isolated prostatic vas deferens. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408672![]() (CHEMBL144000) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 19.5 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair |