BDBM50409723 CHEMBL475089

SMILES: Nc1ncnc2n(cnc12)[C@@H]1CC(F)(F)[C@H](CO)O1

InChI Key: InChIKey=CGYGOMSWJFPRIE-WDSKDSINSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50409723 (CHEMBL475089) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1CC(F)(F)[C@H](CO)O1 |r| Show InChI InChI=1S/C10H11F2N5O2/c11-10(12)1-6(19-5(10)2-18)17-4-16-7-8(13)14-3-15-9(7)17/h3-6,18H,1-2H2,(H2,13,14,15)/t5-,6-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50				J Med Chem 46: 3245-56 (2003) Article DOI: 10.1021/jm0300274 BindingDB Entry DOI: 10.7270/Q20V8C6H
					More data for this Ligand-Target Pair