BDBM50409775 CHEMBL348656

SMILES: C(CCc1cnc[nH]1)CNCCc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1

InChI Key: InChIKey=DBKIPTDCISZMBW-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Cavia porcellus)	BDBM50409775 (CHEMBL348656) Show SMILES C(CCc1cnc[nH]1)CNCCc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1 Show InChI InChI=1S/C27H33N5/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-20-25(32-27)16-18-28-17-8-7-13-24-19-29-21-31-24/h1-6,9-12,19-21,26,28H,7-8,13-18H2,(H,29,31)(H,30,32)	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM50409775 (CHEMBL348656) Show SMILES C(CCc1cnc[nH]1)CNCCc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1 Show InChI InChI=1S/C27H33N5/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-20-25(32-27)16-18-28-17-8-7-13-24-19-29-21-31-24/h1-6,9-12,19-21,26,28H,7-8,13-18H2,(H,29,31)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of...				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair