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BDBM50409980 CHEMBL382962

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3ccccn3)cc2)cc1)c1ccccc1

InChI Key: InChIKey=QPKZOOOOAYTKND-PMERELPUSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409980   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50409980
PNG
(CHEMBL382962)
Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3ccccn3)cc2)cc1)c1ccccc1
Show InChI InChI=1S/C31H30N4O3S2/c36-30(25-6-2-1-3-7-25)21-32-19-17-23-9-13-26(14-10-23)35-40(37,38)27-15-11-24(12-16-27)20-31-34-29(22-39-31)28-8-4-5-18-33-28/h1-16,18,22,30,32,35-36H,17,19-21H2/t30-/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 22n/an/an/an/a



S.G.S.I.T.S.

Curated by ChEMBL


Assay Description
Effective concentration to stimulate cAMP production in chinese hamster ovary cells expressing cloned human beta-3-adrenergic receptor

Bioorg Med Chem Lett 15: 3167-73 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.119
BindingDB Entry DOI: 10.7270/Q26111JS
More data for this
Ligand-Target Pair