BDBM50410859 CHEMBL382880

SMILES: CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H]1CCCCN(Cc2cccc(Nc3ccccc3Cl)c2)C1=O)C(N)=O

InChI Key: InChIKey=JHABJVKRUFEAOR-XFAFFCHDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50410859 (CHEMBL382880) Show SMILES CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H]1CCCCN(Cc2cccc(Nc3ccccc3Cl)c2)C1=O)C(N)=O Show InChI InChI=1S/C30H41ClN4O3/c1-4-10-23(28(32)36)24(17-20(2)3)29(37)34-27-15-7-8-16-35(30(27)38)19-21-11-9-12-22(18-21)33-26-14-6-5-13-25(26)31/h5-6,9,11-14,18,20,23-24,27,33H,4,7-8,10,15-17,19H2,1-3H3,(H2,32,36)(H,34,37)/t23-,24+,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of beta-amyloid peptide production in CHO N9 cell line				Bioorg Med Chem Lett 16: 2357-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.055 BindingDB Entry DOI: 10.7270/Q2WD405K
					More data for this Ligand-Target Pair