Found 4 hits for monomerid = 50410965 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin K
(Homo sapiens (Human)) | BDBM50410965
(CHEMBL376994)Show SMILES CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(o1)-c1cccc(OC)c1 Show InChI InChI=1S/C29H31F3N4O6/c1-3-8-22(23(37)26-36-35-25(41-26)19-9-7-10-21(17-19)40-2)33-27(39)28(15-5-4-6-16-28)34-24(38)18-11-13-20(14-12-18)42-29(30,31)32/h7,9-14,17,22H,3-6,8,15-16H2,1-2H3,(H,33,39)(H,34,38)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celera Genomics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin K |
Bioorg Med Chem Lett 16: 2909-14 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.001
BindingDB Entry DOI: 10.7270/Q2QN6808 |
More data for this
Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50410965
(CHEMBL376994)Show SMILES CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(o1)-c1cccc(OC)c1 Show InChI InChI=1S/C29H31F3N4O6/c1-3-8-22(23(37)26-36-35-25(41-26)19-9-7-10-21(17-19)40-2)33-27(39)28(15-5-4-6-16-28)34-24(38)18-11-13-20(14-12-18)42-29(30,31)32/h7,9-14,17,22H,3-6,8,15-16H2,1-2H3,(H,33,39)(H,34,38)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celera Genomics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin B |
Bioorg Med Chem Lett 16: 2909-14 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.001
BindingDB Entry DOI: 10.7270/Q2QN6808 |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50410965
(CHEMBL376994)Show SMILES CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(o1)-c1cccc(OC)c1 Show InChI InChI=1S/C29H31F3N4O6/c1-3-8-22(23(37)26-36-35-25(41-26)19-9-7-10-21(17-19)40-2)33-27(39)28(15-5-4-6-16-28)34-24(38)18-11-13-20(14-12-18)42-29(30,31)32/h7,9-14,17,22H,3-6,8,15-16H2,1-2H3,(H,33,39)(H,34,38)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celera Genomics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin L |
Bioorg Med Chem Lett 16: 2909-14 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.001
BindingDB Entry DOI: 10.7270/Q2QN6808 |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50410965
(CHEMBL376994)Show SMILES CCC[C@H](NC(=O)C1(CCCCC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)c1nnc(o1)-c1cccc(OC)c1 Show InChI InChI=1S/C29H31F3N4O6/c1-3-8-22(23(37)26-36-35-25(41-26)19-9-7-10-21(17-19)40-2)33-27(39)28(15-5-4-6-16-28)34-24(38)18-11-13-20(14-12-18)42-29(30,31)32/h7,9-14,17,22H,3-6,8,15-16H2,1-2H3,(H,33,39)(H,34,38)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celera Genomics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin S |
Bioorg Med Chem Lett 16: 2909-14 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.001
BindingDB Entry DOI: 10.7270/Q2QN6808 |
More data for this
Ligand-Target Pair | |
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