BDBM50412724 CHEMBL516809::QF-1068B

SMILES: Fc1ccc2c(noc2c1)C1CCN(CC2Cc3oc(cc3C(=O)C2)-c2ccccc2)CC1

InChI Key: InChIKey=VMIRJSPUFWFFPK-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50412724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50412724 (CHEMBL516809 | QF-1068B) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2Cc3oc(cc3C(=O)C2)-c2ccccc2)CC1 Show InChI InChI=1S/C27H25FN2O3/c28-20-6-7-21-26(14-20)33-29-27(21)19-8-10-30(11-9-19)16-17-12-23(31)22-15-24(32-25(22)13-17)18-4-2-1-3-5-18/h1-7,14-15,17,19H,8-13,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human cloned 5HT2A receptor				J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50412724 (CHEMBL516809 | QF-1068B) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2Cc3oc(cc3C(=O)C2)-c2ccccc2)CC1 Show InChI InChI=1S/C27H25FN2O3/c28-20-6-7-21-26(14-20)33-29-27(21)19-8-10-30(11-9-19)16-17-12-23(31)22-15-24(32-25(22)13-17)18-4-2-1-3-5-18/h1-7,14-15,17,19H,8-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2 receptor				J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50412724 (CHEMBL516809 | QF-1068B) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2Cc3oc(cc3C(=O)C2)-c2ccccc2)CC1 Show InChI InChI=1S/C27H25FN2O3/c28-20-6-7-21-26(14-20)33-29-27(21)19-8-10-30(11-9-19)16-17-12-23(31)22-15-24(32-25(22)13-17)18-4-2-1-3-5-18/h1-7,14-15,17,19H,8-13,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human cloned 5HT2C receptor				J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72
					More data for this Ligand-Target Pair