BDBM50413760 CHEMBL426020
SMILES: CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O
InChI Key: InChIKey=WQSCKYAATADRBI-NCQVFETRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Urotensin II receptor (Homo sapiens (Human)) | BDBM50413760 (CHEMBL426020) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human UT2 receptor expressed in CHO-K1 cells by liquid scintillation counting | J Med Chem 52: 3927-40 (2009) Article DOI: 10.1021/jm900148c BindingDB Entry DOI: 10.7270/Q27W6DFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin II receptor (Homo sapiens (Human)) | BDBM50413760 (CHEMBL426020) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Ability to displace radioligand [125I]Tyr-hU-II from human recombinant Urotensin 2 receptor in CHO-K1 cells | J Med Chem 45: 4391-4 (2002) Article DOI: 10.1021/jm025549i BindingDB Entry DOI: 10.7270/Q2FR00C5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin II receptor (Homo sapiens (Human)) | BDBM50413760 (CHEMBL426020) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno Curated by ChEMBL | Assay Description Binding affinity towards human Urotensin 2 receptor was determined | J Med Chem 47: 1652-61 (2004) Article DOI: 10.1021/jm0309912 BindingDB Entry DOI: 10.7270/Q26W9DS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UTS2R (RAT) | BDBM50413760 (CHEMBL426020) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Agonist activity at UT2 receptor in Albino rat aorta assessed as induction of aortic contraction | J Med Chem 52: 3927-40 (2009) Article DOI: 10.1021/jm900148c BindingDB Entry DOI: 10.7270/Q27W6DFT | |||||||||||
More data for this Ligand-Target Pair |