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SMILES: Cc1cccc(C)c1N1CN2CCC[C@@H]2C1=O

InChI Key: InChIKey=GKUMGUUVSHJTIU-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413855   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 4 subunit alpha


(Homo sapiens (Human))		BDBM50413855
PNG
(CHEMBL501346)
Show SMILES Cc1cccc(C)c1N1CN2CCC[C@@H]2C1=O |r|
Show InChI InChI=1S/C14H18N2O/c1-10-5-3-6-11(2)13(10)16-9-15-8-4-7-12(15)14(16)17/h3,5-6,12H,4,7-9H2,1-2H3/t12-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 5.01E+5n/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current

Eur J Med Chem 44: 1477-85 (2009)


Article DOI: 10.1016/j.ejmech.2008.10.005
BindingDB Entry DOI: 10.7270/Q2M61MGC
More data for this
Ligand-Target Pair