Found 6 hits for monomerid = 50414559 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human DRD2 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human DRD3 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414559
(CHEMBL557110)Show SMILES Clc1cccc(c1)N1CCN(CCN2CCCC(C2)OCc2ccccc2)C1=O Show InChI InChI=1S/C23H28ClN3O2/c24-20-8-4-9-21(16-20)27-15-14-26(23(27)28)13-12-25-11-5-10-22(17-25)29-18-19-6-2-1-3-7-19/h1-4,6-9,16,22H,5,10-15,17-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Displacement of [3H]dofetilide from human ERG |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
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