BindingDB PrimarySearch_ki

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Enter Data

BDBM50414857 CHEMBL576586

SMILES: Clc1cccc(c1)N1CCN(CCCn2cnc3ccccc3c2=O)CC1

InChI Key: InChIKey=QRTNQVOGBIPAAV-UHFFFAOYSA-N

Data: 2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414857
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50414857 (CHEMBL576586) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-HT2A receptor in Wistar Hannover rat brain cortex membrane				Eur J Med Chem 44: 5045-54 (2009) Article DOI: 10.1016/j.ejmech.2009.09.008 BindingDB Entry DOI: 10.7270/Q2BG2Q6P
University of Porto Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50414857 (CHEMBL576586) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cells after 120 mins				Eur J Med Chem 44: 5045-54 (2009) Article DOI: 10.1016/j.ejmech.2009.09.008 BindingDB Entry DOI: 10.7270/Q2BG2Q6P
University of Porto Curated by ChEMBL					More data for this Ligand-Target Pair