BDBM50414860 CHEMBL574604

SMILES: COc1ccccc1N1CCN(CCCCn2n(-c3ccccc3)c(=O)ccc2=O)CC1

InChI Key: InChIKey=RBLFCZAQJBFHEJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50414860 (CHEMBL574604) Show SMILES COc1ccccc1N1CCN(CCCCn2n(-c3ccccc3)c(=O)ccc2=O)CC1 Show InChI InChI=1S/C25H30N4O3/c1-32-23-12-6-5-11-22(23)27-19-17-26(18-20-27)15-7-8-16-28-24(30)13-14-25(31)29(28)21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cells after 120 mins				Eur J Med Chem 44: 5045-54 (2009) Article DOI: 10.1016/j.ejmech.2009.09.008 BindingDB Entry DOI: 10.7270/Q2BG2Q6P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50414860 (CHEMBL574604) Show SMILES COc1ccccc1N1CCN(CCCCn2n(-c3ccccc3)c(=O)ccc2=O)CC1 Show InChI InChI=1S/C25H30N4O3/c1-32-23-12-6-5-11-22(23)27-19-17-26(18-20-27)15-7-8-16-28-24(30)13-14-25(31)29(28)21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-HT2A receptor in Wistar Hannover rat brain cortex membrane				Eur J Med Chem 44: 5045-54 (2009) Article DOI: 10.1016/j.ejmech.2009.09.008 BindingDB Entry DOI: 10.7270/Q2BG2Q6P
					More data for this Ligand-Target Pair