BDBM50415245 CHEMBL593894

SMILES: Cc1cc(cc2c(Nc3cccc(c3)C#N)c(C(N)=O)c(=O)[nH]c12)S(C)(=O)=O

InChI Key: InChIKey=GAYKGDPZVZGEJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50415245 (CHEMBL593894) Show SMILES Cc1cc(cc2c(Nc3cccc(c3)C#N)c(C(N)=O)c(=O)[nH]c12)S(C)(=O)=O Show InChI InChI=1S/C19H16N4O4S/c1-10-6-13(28(2,26)27)8-14-16(10)23-19(25)15(18(21)24)17(14)22-12-5-3-4-11(7-12)9-20/h3-8H,1-2H3,(H2,21,24)(H2,22,23,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain by scintillation proximity assay				Bioorg Med Chem Lett 20: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.11.010 BindingDB Entry DOI: 10.7270/Q2RJ4KPG
					More data for this Ligand-Target Pair