BDBM50416878 CHEMBL1256404

SMILES: CC(O)(c1nc2ccccc2s1)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ZWGQBVNTUHZGNM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50416878 (CHEMBL1256404) Show SMILES CC(O)(c1nc2ccccc2s1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H11Cl2NOS/c1-15(19,10-7-6-9(16)8-11(10)17)14-18-12-4-2-3-5-13(12)20-14/h2-8,19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by cell based assay				Bioorg Med Chem Lett 20: 5918-21 (2010) Article DOI: 10.1016/j.bmcl.2010.07.077 BindingDB Entry DOI: 10.7270/Q22J6D4S
					More data for this Ligand-Target Pair