BDBM50416921 CHEMBL1258292

SMILES: CCCSc1nnc-2c(O[C@@H](CC)N(C(C)=O)c3ccccc-23)n1

InChI Key: InChIKey=DBHDXCQPYAWCQQ-AWEZNQCLSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50416921 (CHEMBL1258292) Show SMILES CCCSc1nnc-2c(O[C@@H](CC)N(C(C)=O)c3ccccc-23)n1 |r| Show InChI InChI=1S/C17H20N4O2S/c1-4-10-24-17-18-16-15(19-20-17)12-8-6-7-9-13(12)21(11(3)22)14(5-2)23-16/h6-9,14H,4-5,10H2,1-3H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.76E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells				Bioorg Med Chem Lett 20: 5922-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3
					More data for this Ligand-Target Pair