BDBM50418034 CHEMBL1230217

SMILES: OC(=O)CNC(=O)c1nc2cc(Cl)c(Cl)cc2[nH]1

InChI Key: InChIKey=ALMZPAHRESNZRJ-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50418034 (CHEMBL1230217) Show SMILES OC(=O)CNC(=O)c1nc2cc(Cl)c(Cl)cc2[nH]1 Show InChI InChI=1S/C10H7Cl2N3O3/c11-4-1-6-7(2-5(4)12)15-9(14-6)10(18)13-3-8(16)17/h1-2H,3H2,(H,13,18)(H,14,15)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PHD2				ACS Med Chem Lett 1: 526-529 (2010) Article DOI: 10.1021/ml100198y BindingDB Entry DOI: 10.7270/Q28053VF
					More data for this Ligand-Target Pair				3D Structure (crystal)