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BDBM50418074 CHEMBL1688939

SMILES: C(Cn1cc(Cc2ccccc2)nn1)c1cnc[nH]1

InChI Key: InChIKey=ALQGNVPKKTWRPO-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418074   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50418074
PNG
(CHEMBL1688939)
Show SMILES C(Cn1cc(Cc2ccccc2)nn1)c1cnc[nH]1
Show InChI InChI=1S/C14H15N5/c1-2-4-12(5-3-1)8-14-10-19(18-17-14)7-6-13-9-15-11-16-13/h1-5,9-11H,6-8H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
380n/an/an/an/an/an/an/an/a



VU University Amsterdam

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting


J Med Chem 54: 1693-703 (2011)


Article DOI: 10.1021/jm1013488
BindingDB Entry DOI: 10.7270/Q20G3MDD
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50418074
PNG
(CHEMBL1688939)
Show SMILES C(Cn1cc(Cc2ccccc2)nn1)c1cnc[nH]1
Show InChI InChI=1S/C14H15N5/c1-2-4-12(5-3-1)8-14-10-19(18-17-14)7-6-13-9-15-11-16-13/h1-5,9-11H,6-8H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.15E+3n/an/an/an/an/an/an/an/a



VU University Amsterdam

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting


J Med Chem 54: 1693-703 (2011)


Article DOI: 10.1021/jm1013488
BindingDB Entry DOI: 10.7270/Q20G3MDD
More data for this
Ligand-Target Pair