BDBM50419211 CHEMBL1834679

SMILES: Fc1cc(F)cc(NC(=O)CN(C2CCCC2)C(=O)c2ccc(cc2)-c2ccccn2)c1

InChI Key: InChIKey=LOGJGOFZLXSFLX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50419211 (CHEMBL1834679) Show SMILES Fc1cc(F)cc(NC(=O)CN(C2CCCC2)C(=O)c2ccc(cc2)-c2ccccn2)c1 Show InChI InChI=1S/C25H23F2N3O2/c26-19-13-20(27)15-21(14-19)29-24(31)16-30(22-5-1-2-6-22)25(32)18-10-8-17(9-11-18)23-7-3-4-12-28-23/h3-4,7-15,22H,1-2,5-6,16H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay				Bioorg Med Chem Lett 21: 6176-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.096 BindingDB Entry DOI: 10.7270/Q2251KF6
					More data for this Ligand-Target Pair