BDBM50419413 CHEMBL1915014

SMILES: CCCc1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)c2o1

InChI Key: InChIKey=AFJWGPROQZBGGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50419413 (CHEMBL1915014) Show SMILES CCCc1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)c2o1 Show InChI InChI=1S/C17H17ClN2O3/c1-3-4-14-8-11-6-13(18)7-12(16(11)23-14)9-20-10(2)5-15(19-20)17(21)22/h5-8H,3-4,9H2,1-2H3,(H,21,22)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]GW875240X from human prostanoid EP1 receptor expressed in CHO-K1 cells after 45 mins by topcount liquid scintillation counting				Bioorg Med Chem Lett 21: 4343-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.047 BindingDB Entry DOI: 10.7270/Q2RN394N
					More data for this Ligand-Target Pair