BDBM50419428 CHEMBL1915736

SMILES: COc1cccnc1COc1ccc(cc1)-c1nn(CCF)cc1-c1ccncc1

InChI Key: InChIKey=SIVBTGBSMDUKON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM50419428 (CHEMBL1915736) Show SMILES COc1cccnc1COc1ccc(cc1)-c1nn(CCF)cc1-c1ccncc1 Show InChI InChI=1S/C23H21FN4O2/c1-29-22-3-2-11-26-21(22)16-30-19-6-4-18(5-7-19)23-20(15-28(27-23)14-10-24)17-8-12-25-13-9-17/h2-9,11-13,15H,10,14,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...				J Med Chem 54: 5820-35 (2011) Article DOI: 10.1021/jm200536d BindingDB Entry DOI: 10.7270/Q2NV9JNP
					More data for this Ligand-Target Pair