BDBM50419435 CHEMBL1915745

SMILES: COc1ccc(Br)c(COc2ccc(cc2)-c2nn(CCF)cc2-c2ccncc2)n1

InChI Key: InChIKey=YRPVOUBCSHQTDH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM50419435 (CHEMBL1915745) Show SMILES COc1ccc(Br)c(COc2ccc(cc2)-c2nn(CCF)cc2-c2ccncc2)n1 Show InChI InChI=1S/C23H20BrFN4O2/c1-30-22-7-6-20(24)21(27-22)15-31-18-4-2-17(3-5-18)23-19(14-29(28-23)13-10-25)16-8-11-26-12-9-16/h2-9,11-12,14H,10,13,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...				J Med Chem 54: 5820-35 (2011) Article DOI: 10.1021/jm200536d BindingDB Entry DOI: 10.7270/Q2NV9JNP
					More data for this Ligand-Target Pair