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SMILES: Oc1c(Sc2ccccc2)cc(NS(=O)(=O)c2cccs2)c2ccccc12

InChI Key: InChIKey=ANWROCYWIBTMKJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM50420788
PNG
(CHEMBL2088019)
Show SMILES Oc1c(Sc2ccccc2)cc(NS(=O)(=O)c2cccs2)c2ccccc12
Show InChI InChI=1S/C20H15NO3S3/c22-20-16-10-5-4-9-15(16)17(21-27(23,24)19-11-6-12-25-19)13-18(20)26-14-7-2-1-3-8-14/h1-13,21-22H
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n/an/a 570n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assay

J Med Chem 55: 5220-30 (2012)


Article DOI: 10.1021/jm3004416
BindingDB Entry DOI: 10.7270/Q2ZC8451
More data for this
Ligand-Target Pair