BDBM50421491 CHEMBL60445::ORG-24668

SMILES: CN(CCC(Oc1ccc(Cl)c(Cl)c1)c1ccccc1)CC([O-])=O

InChI Key: InChIKey=APNYNODJCWEDNP-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50421491 (CHEMBL60445 | ORG-24668) Show SMILES CN(CCC(Oc1ccc(Cl)c(Cl)c1)c1ccccc1)CC([O-])=O Show InChI InChI=1S/C18H19Cl2NO3/c1-21(12-18(22)23)10-9-17(13-5-3-2-4-6-13)24-14-7-8-15(19)16(20)11-14/h2-8,11,17H,9-10,12H2,1H3,(H,22,23)/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Organon Research and Development Group Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporter				Bioorg Med Chem Lett 11: 2007-9 (2001) BindingDB Entry DOI: 10.7270/Q2X0687Q
					More data for this Ligand-Target Pair