BindingDB logo
myBDB logout

null

SMILES: [O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2CCCOC2=O)cc1

InChI Key: InChIKey=STKHWLHESIEASL-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421615   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))		BDBM50421615
PNG
(CHEMBL132173)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2CCCOC2=O)cc1
Show InChI InChI=1S/C25H25N3O5/c29-25-27(15-2-16-32-25)23(8-5-19-11-13-26-14-12-19)18-33-24-9-6-20(7-10-24)21-3-1-4-22(17-21)28(30)31/h1,3-4,6-7,9-14,17,23H,2,5,8,15-16,18H2
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 631n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.

Bioorg Med Chem Lett 13: 4043-6 (2003)


BindingDB Entry DOI: 10.7270/Q2930VCQ
More data for this
Ligand-Target Pair