BDBM50422260 CHEMBL6566

SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)c(C)n1

InChI Key: InChIKey=QBKBVEQZXPNGQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50422260 (CHEMBL6566) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)c(C)n1 Show InChI InChI=1S/C18H18BrN3O2S/c1-12-15(19)10-11-18(20-12)21-25(23,24)17-9-5-6-13-14(17)7-4-8-16(13)22(2)3/h4-11H,1-3H3,(H,20,21)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor				J Med Chem 40: 996-1004 (1997) Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT
					More data for this Ligand-Target Pair