BDBM50424336 CHEMBL2314776

SMILES: COc1ccc(cc1)-c1cc2c(nc(N)nc2[nH]1)N1CCN(C)CC1

InChI Key: InChIKey=DAOZOMZYCFJQIE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50424336 (CHEMBL2314776) Show SMILES COc1ccc(cc1)-c1cc2c(nc(N)nc2[nH]1)N1CCN(C)CC1 Show InChI InChI=1S/C18H22N6O/c1-23-7-9-24(10-8-23)17-14-11-15(20-16(14)21-18(19)22-17)12-3-5-13(25-2)6-4-12/h3-6,11H,7-10H2,1-2H3,(H3,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma				Bioorg Med Chem Lett 23: 132-7 (2012) Article DOI: 10.1016/j.bmcl.2012.10.139 BindingDB Entry DOI: 10.7270/Q28P61TF
					More data for this Ligand-Target Pair