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SMILES: COc1ccc2c(c1)oc1c(Nc3ccc4OCCOc4c3)ncnc21

InChI Key: InChIKey=IFJPCGIEIHVPKT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424702 (CHEMBL2313886) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc4OCCOc4c3)ncnc21 Show InChI InChI=1S/C19H15N3O4/c1-23-12-3-4-13-15(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-16(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50424702 (CHEMBL2313886) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc4OCCOc4c3)ncnc21 Show InChI InChI=1S/C19H15N3O4/c1-23-12-3-4-13-15(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-16(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424702 (CHEMBL2313886) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc4OCCOc4c3)ncnc21 Show InChI InChI=1S/C19H15N3O4/c1-23-12-3-4-13-15(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-16(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair