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BDBM50424799 CHEMBL2315133

SMILES: Cc1ccc(C)c(c1)C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1

InChI Key: InChIKey=KOCLPXHENKOLAS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Mus musculus)		BDBM50424799
PNG
(CHEMBL2315133)
Show SMILES Cc1ccc(C)c(c1)C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1
Show InChI InChI=1S/C23H29N5O2/c1-16-3-4-17(2)19(15-16)23(30)28-13-11-27(12-14-28)21-8-7-20(25-26-21)22(29)24-10-9-18-5-6-18/h3-4,7-8,15,18H,5-6,9-14H2,1-2H3,(H,24,29)
PDB

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UniProtKB/TrEMBL

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UniChem

Similars
Article
PubMed
n/an/a 942n/an/an/an/an/an/a



Xenon Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...

J Med Chem 56: 568-83 (2013)


Article DOI: 10.1021/jm301661h
BindingDB Entry DOI: 10.7270/Q25Q4XDG
More data for this
Ligand-Target Pair