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SMILES: CN(C)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1

InChI Key: InChIKey=YIOLCQFUHDXWJC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424805   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Mus musculus)		BDBM50424805
PNG
(CHEMBL2315127)
Show SMILES CN(C)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1
Show InChI InChI=1S/C23H30N6O2/c1-27(2)20-6-4-3-5-18(20)23(31)29-15-13-28(14-16-29)21-10-9-19(25-26-21)22(30)24-12-11-17-7-8-17/h3-6,9-10,17H,7-8,11-16H2,1-2H3,(H,24,30)
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UniProtKB/SwissProt

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PC cid
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UniChem
Article
PubMed
n/an/a 920n/an/an/an/an/an/a



Xenon Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...

J Med Chem 56: 568-83 (2013)


Article DOI: 10.1021/jm301661h
BindingDB Entry DOI: 10.7270/Q25Q4XDG
More data for this
Ligand-Target Pair