BDBM50424811 CHEMBL2315122

SMILES: FC(F)(F)c1occc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1

InChI Key: InChIKey=RCVPUPWQGZXUEJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase 1 (Homo sapiens (Human))	BDBM50424811 (CHEMBL2315122) Show SMILES FC(F)(F)c1occc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1 Show InChI InChI=1S/C20H22F3N5O3/c21-20(22,23)17-14(6-12-31-17)19(30)28-10-8-27(9-11-28)16-4-3-15(25-26-16)18(29)24-7-5-13-1-2-13/h3-4,6,12-13H,1-2,5,7-11H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs				J Med Chem 56: 568-83 (2013) Article DOI: 10.1021/jm301661h BindingDB Entry DOI: 10.7270/Q25Q4XDG
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Mus musculus)	BDBM50424811 (CHEMBL2315122) Show SMILES FC(F)(F)c1occc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCCC1CC1 Show InChI InChI=1S/C20H22F3N5O3/c21-20(22,23)17-14(6-12-31-17)19(30)28-10-8-27(9-11-28)16-4-3-15(25-26-16)18(29)24-7-5-13-1-2-13/h3-4,6,12-13H,1-2,5,7-11H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...				J Med Chem 56: 568-83 (2013) Article DOI: 10.1021/jm301661h BindingDB Entry DOI: 10.7270/Q25Q4XDG
					More data for this Ligand-Target Pair