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SMILES: CC(C)CCNC(=O)c1cnc(cn1)N1CCN(CC1)C(=O)c1ccccc1C(F)(F)F

InChI Key: InChIKey=DZPFDWOHVKGPOK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Mus musculus)		BDBM50424832
PNG
(CHEMBL2315091)
Show SMILES CC(C)CCNC(=O)c1cnc(cn1)N1CCN(CC1)C(=O)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C22H26F3N5O2/c1-15(2)7-8-26-20(31)18-13-28-19(14-27-18)29-9-11-30(12-10-29)21(32)16-5-3-4-6-17(16)22(23,24)25/h3-6,13-15H,7-12H2,1-2H3,(H,26,31)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Xenon Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...

J Med Chem 56: 568-83 (2013)


Article DOI: 10.1021/jm301661h
BindingDB Entry DOI: 10.7270/Q25Q4XDG
More data for this
Ligand-Target Pair