BDBM50425265 CHEMBL2315479

SMILES: FC(F)(F)c1cccc(CN2CCC3(CCN(CC3)c3ccc(cn3)C(=O)NCCC3CC3)Oc3ccccc23)c1

InChI Key: InChIKey=ZXRFKHLXQWWOFK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase 1 (SCD1) (Rattus norvegicus (Rat))	BDBM50425265 (CHEMBL2315479) Show SMILES FC(F)(F)c1cccc(CN2CCC3(CCN(CC3)c3ccc(cn3)C(=O)NCCC3CC3)Oc3ccccc23)c1 Show InChI InChI=1S/C32H35F3N4O2/c33-32(34,35)26-5-3-4-24(20-26)22-39-19-15-31(41-28-7-2-1-6-27(28)39)13-17-38(18-14-31)29-11-10-25(21-37-29)30(40)36-16-12-23-8-9-23/h1-7,10-11,20-21,23H,8-9,12-19,22H2,(H,36,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat SCD1 by rat microsomal assay				Bioorg Med Chem Lett 23: 791-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.075 BindingDB Entry DOI: 10.7270/Q26H4JQ6
					More data for this Ligand-Target Pair